Teaching

Molecules, Genes and Cells (BIOL 191)


Taught in Fall 2019, Spring 2020

An introduction to the molecular and cellular processes common to life with an emphasis on control of energy and information flow. Central themes include metabolism, macromolecular function, and the genetic basis of cellular function. We examine how membranes work to establish the internal composition of cells; how the structure of proteins including enzymes affects protein function; how energy is captured, stored and utilized by cells; and how cells communicate, move and divide. We explore inheritance patterns and underlying molecular mechanisms of genetics, the central dogma of information transfer from DNA replication to protein synthesis, and recombinant DNA methods and medical applications. Laboratories include genetic analyses, enzyme reaction kinetics, membrane transport, and genomic analysis.COVID in the Classroom BIOL191: Student Reflections

Biochemistry with Lab (BIOL/BCBP/CHEM 331)


Taught in Spring 2016, Spring 2017, Spring 2018, Spring 2022

Structure and function of biologically important molecules and their role(s) in life processes. Protein conformation, enzymatic mechanisms and selected metabolic pathways will be analyzed. Additional topics may include: nucleic acid conformation, DNA/protein interactions, signal transduction and transport phenomena. Offered jointly by the Departments of Biology and Chemistry.

Molecular Genetics with Lab (BIOL 371, BCBP 371)


Taught in Fall 2015, Fall 2016, Fall 2017, Fall 2020, Fall 2021

A study of the molecular mechanisms underlying the transmission and expression of genes. DNA replication and recombination, RNA synthesis and processing, and protein synthesis and modification will be examined. Both prokaryotic and eukaryotic systems will be analyzed, with an emphasis upon the regulation of gene expression. Application of modern molecular methods to biomedical problems will also be considered.

Seminar in Biology of Metals: A Molecular/Cellular Perspective (BIOL 470)


Taught in Spring 2016, Spring 2021, Spring 2022

Metals are required for the function of about one third of all proteins and are involved in vital biological processes such as photosynthesis, respiration, gene regulation, DNA replication and repair, signal transduction, and antioxidant defense. However, essential metals are potentially toxic due to the same properties that make them indispensable. To cope with such a paradox, metals must be tightly regulated.

This advanced seminar will focus on the molecular and cellular biology of metals. Topics of discussion will include metal homeostasis strategies (e.g. import/export, chelation, subcellular compartmentalization), metal cofactors of biochemical processes, inherited metal metabolism disorders, and genetics of hyperaccumulators. We will also discuss prospects of manipulating metal homeostasis to aid human health and environmental sustainability.